- January 30, 2026
Primary Amenorrhea: Pathophysiology, Causes, and Impact on Health
Share with your friends
About Dr. Rashmi Sharma
Dr. Rashmi Sharma is an IVF specialist, Consultant Reproductive Medicine, and Director Origyn Fertility & IVF, New Delhi. She holds MBBS (BHU), MD (BHU), DNB, MNAMS, FICOG, and a Diploma in IVF & Reproductive Medicine (Kiel University, Germany). Web Editor, Indian Fertility Society (2024–26). Former HOD, IVF Department, Moolchand Hospital, Delhi (2009–13) and Max Hospital, Pitampura, Delhi (2013–17). Director, Origyn Fertility & IVF, which has 4 branches across Delhi.
Origyn IVF has been accredited for a 1-year fellowship in IVF and Reproductive Medicine, along with an MSc in Clinical Embryology under Amity University and IFS collaboration.
Recipient of the “C. S. Dawn Award” for best paper presentation on IVF/ICSI with genital tuberculosis at the All India Congress of Obstetrics and Gynecology (AICOG 2010).
Recipient of the “Hall of Fame – Best IVF Specialist in India – North” at the Economic Times National Fertility Awards in 2019, 2023, and 2024.
Origyn IVF received the “Best IVF Center in North India” and “Most Integrated Team in IVF – North” at the Economic Times National Fertility Awards in 2019 and 2024.
Recipient of the “Best IFS Executive” award at Fertivision 2018, Kochi. Authored various chapters in reputed infertility textbooks with numerous national and international publications and presentations.
Contact Us
Primary amenorrhea
Primary Amenorrhea can be considered as either the Absence of menstrual period by the age of 14 years when the secondary sexual characteristics do not develop.
OR
Absence of menstruation by 16 years of age regardless of the presence of normal growth and development of secondary sexual characteristics.
PATHOPHYSIOLOGY OF MENSTRUAL BLEEDING
The levels of oestrogen in the body stimulate the proliferation of endometrium.
After ovulation, the Corpus luteum develops and starts to produce the hormone progesterone which causes the transformation of the proliferating endometrium into secretory.
In the absence of pregnancy, the secretory endometrium sheds in the form of menstrual bleeding.
Understanding Infertility and Why Expert Care Matters
Infertility is a complex and emotionally challenging condition that can affect both physical health and mental well-being. Identifying the root cause is crucial, as timely expert care ensures accurate diagnosis and personalized treatment. With the right medical guidance, individuals and couples receive not only effective solutions but also the emotional support needed throughout their fertility journey.
Common causes are:
- Hormonal imbalances
- Ovulation disorders
- A low sperm count or low-quality sperm
- Blocked fallopian tubes
- Endometriosis
- Lifestyle and stress-related problems
Because infertility does not have only one reason, seeking out an infertility specialist in delhi. A specialist can pinpoint the cause and formulate a suitable treatment plan that addresses the root of the issue, not just any symptoms.
Why Choose the Best Infertility Specialist in Delhi
Delhi is a leading hub for fertility treatment, combining expert medical care with advanced technology.Patients from across different regions choose Origyn IVF for its expert infertility specialist in Delhi, advanced facilities, and comprehensive fertility care options.
- Access to Advanced Technology
Fertility clinics treatments in Delhi are outfitted with the most modern diagnostic tools, the most advanced IVF labs and the most modern assisted reproductive technologies. This permits an accurate diagnosis as well as increased treatment with higher success rates.
- Highly Experienced Specialists
An infertility specialist in Delhi is typically a specialist who has years of experience in dealing with difficult fertility problems. Their knowledge of different patients can help them create a more customized treatment plan.
Personalized Fertility Treatment and Its Benefits
Every couple’s path to conception is different for every couple. What works for one couple may not be the same for the other. This is why individual fertility treatments are crucial. The infertility specialist in Delhi are focusing on understanding the medical history of each patient and their lifestyle and emotional needs before deciding on the best treatment plan.
Finding the top fertility doctor in Delhi can make a significant impact in achieving positive results and in fostering hope toward the next.
A customized method takes into consideration:
- Alter and reserve of the ovarian gland
- Hormonal profile
- The background of surgical and medical procedures
- Lifestyle aspects
- Emotional and mental health
The best infertility specialist in Delhi takes time to understand these factors before starting any treatment. Instead of following a routine approach, the treatment plan is customized at Origyn IVF to improve the chances of conception while also reducing physical and emotional stress.